MINIMALLY INVASIVE LS Study Group
STUDY GROUP LEADERS
Alfred Kow (National University of Singapore, Singapore)
Fernando Rotellar (University of Navarra, Pamplona, Spain)
TITLE: Results of the laparoscopic extended cholecystectomy in Gallbladder cancer. A Multi-institutional retrospective Propensity Score Matching Study.
To gather numerous cohort of open and laparoscopic radical resection for gallbladder cancer to provide solid evidence on the operative, short, and oncological outcomes.
The primary endpoint is to define intraoperative (surgery time, conversion, bleeding, intraop. transfusion, margins, number of lymph nodes…), short-term (morbidity rates based on the comprehensive complication index, hospital stay, global transfusion rates, …), and oncological outcomes of a large series of laparoscopic radical resection for gallbladder cancer. Subanalysis will be performed for those cases that underwent reoperation after incidental gallbladder carcinoma found after standard cholecystectomy.
The secondary endpoint is to perform a Propensity Score Matching comparative study of Laparoscopic vs Open radical Gallbladder resection.
STUDY DESIGN: Retrospective Propensity Score Matching study
All high-volume HPB units maintaining a prospective database in open and laparoscopic liver surgery and experience in radical resection for Gallbladder cancer will be invited to participate. All demographic, intraoperative, and 90-days morbidity (based on CCI) data of all adult patients undergoing radical resection for Gallbladder cancer from January 1, 2009, to December 31, 2019, will be collected. The long-term oncological outcome will also be collected and evaluated.
PARTICIPANTS: International multi-center
All centers with experience in open and minimally invasive Gallbladder cancer extended resection are invited to take part on this study.