LDLT-DONOR Study Group
STUDY GROUP LEADERS
Prashant Bhangui (Medanta Institute, India)
Dong Hwan Jung (Asan Medical Center, Korea)
TITLE: Impact of complex bilio-vascular donor anatomy on donor and recipient morbidity in adult LDLT
• This study aims to determine the differences in the incidence of bilio-vascular complications and morbidity in recipients of LDLT receiving grafts from donors with complex bilio-vascular anatomy, compared to those receiving grafts with single artery, portal vein, bile duct.
• To determine whether the presence of complex bilio-vascular anatomy has an impact on donor complications, and adds to donor morbidity.
• To determine whether number (of graft artery/PV/ducts), type (according to the classification of bilio-vascular donor anatomy), or type of anastomoses (using loupes vs. microscope for artery and bile duct, plasty with straight extension vs. Y graft in PV, duct to duct vs. Roux for multiple ducts etc.) determine the incidence of complications.
• To determine whether complications have an impact on long term graft and patient outcomes.
STUDY DESIGN: Retrospective
PARTICIPANTS: International multi-center
1. Right lobe or left lobe LDLT in adults
2. Donor and recipient selection as per Center Policy
3. LDLT performed from January 2014 to December 2018
4. Minimum follow up post LDLT – 1 year
5. Open donor hepatectomy
1. Minimally invasive donor hepatectomy
2. Less than 1 year follow up in donors and recipients (except in case of post operative deaths)
3. Aborted donor or recipient surgeries
1. As per center protocol for donor and recipient
2. Main outcomes – post operative morbidity (Clavien-Dindo Classification), post operative mortality, post operative as well as long term biliary complications, vascular complications, morbidity, mortality.